Published: 30 June 2022

Safety Information

Alert Communication

Patients should keep taking their Accuretic medicine until they have spoken to their healthcare professional.

Accuretic found to contain nitrosamines

Accuretic (quinapril + hydrochlorothiazide) is being withdrawn from use because it contains impurities called nitrosamines. This is a global issue. Pfizer, the supplier of Accuretic, has been undertaking voluntary recalls of the medicine around the world, including in Australia, Europe, the United States of America and Canada.

Advice for consumers and caregivers

Accuretic supply in New Zealand is about to be disrupted. If you are taking Accuretic, you will need to contact your health care professional and discuss changing to an alternative high blood pressure medicine as soon as possible. Keep taking Accuretic until you have spoken to your healthcare professional.

There is no known immediate health risk associated with nitrosamines. If taken long-term, nitrosamines may increase a person’s risk of getting cancer.

See the Pharmac website for more information about the Accuretic supply issue.

Medsafe cannot give advice about an individual’s medical condition. Talk to your healthcare professional if you have any concerns about a medicine you are taking.

Information for healthcare professionals

As Accuretic will soon no longer be available in New Zealand, all patients will need to be switched to an alternative treatment. See the Pharmac website for more information about funded, alternative treatment options.

Please report any adverse events to the Centre for Adverse Reactions Monitoring.

Products affected

Product name Sponsor
Accuretic 12.5mg/10mg Film coated tablets Pfizer New Zealand Limited
Accuretic 12.5mg/20mg Film coated tablets Pfizer New Zealand Limited

Further information

Nitrosamines are a type of N-nitroso compound. These compounds are commonly found in low levels in water and foods, including smoked and cured meats, dairy products and vegetables. Long-term exposure, over many years, may increase a person’s risk of developing cancer.

The presence of nitrosamines in some medicines was first identified in 2018 and is still being investigated globally.

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