Published: 6 June 2013

Withdrawal Symptoms After Use of Hyoscine Patches

Prescriber Update 34(2):24
June 2013

The Centre for Adverse Reactions Monitoring (CARM) has received three reports of withdrawal symptoms in patients after using hyoscine patches for prevention of nausea. In all three reports, the withdrawal symptoms occurred after the hyoscine patches were used for more than three days.

Reported symptoms included nausea and vomiting, headache, balance disorders (vertigo), dizziness and blurred vision. In one case, it was reported that these symptoms resolved after reapplication of the patch. Overall, these symptoms make take several days to settle after patch removal.

Healthcare professionals should advise patients of the risk of withdrawal symptoms and counsel patients not to drive or operate machinery if they experience such symptoms.